ISSN 1305-3825 | E-ISSN 1305-3612
1 Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt am Main, Frankfurt am Main, Germany.  
2 Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt am Main, Frankfurt am Main, Germany; Department of Radiology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania  
3 Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt am Main, Frankfurt am Main, Germany; Department of Diagnostic and Interventional Radiology, Cairo University Hospital, Cairo, Egypt  
4 Medical Clinic I, “Fuerth’’ Hospital, University of Erlangen, Fuerth, Germany  
5 Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt am Main, Frankfurt am Main, Germany; Institute of Diagnostic Radiology, Department of Biological and Medical Sciences, University of Udine, Udine, Italy  
Diagn Interv Radiol 2017; 23: -

Abstract

Purpose: To retrospectively compare the local tumor control rates between a low frequency (LF) and a high frequency (HF) microwave ablation device in the treatment of lung metastases <3 cm.

 

Methods: Thirty six patients (55 tumors) were treated with the LF system (915 MHz) and 30 patients (39 tumors) were treated with the HF system (2450 MHz) between January 2011 and March 2016. A CT performed just before the ablation and one 24 hours after were used to measure the size of the ablation zone and to calculate the safety margin. The subsequent CTs were used to detect local tumor progression. Possible predictive factors for local progression were analyzed. All patients had a minimum follow-up of 3 months with a median of 13.8 months for the LF group and 11.7 months for the HF group.

 

Results: The ablation margin (p=0.015), blood vessel proximity (p=0.006), and colorectal origin (p=0.029) were significantly associated with the local progression rate. The local progression rates were 36.3% for the LF ablations and 12.8% for the HF ablations. The 6, 12 and 18 months local progression free survival rates were 79.0%, 65.2% and 53.0% for the LF group and 97.1%, 93.7 % and 58.4 % respectively for the HF group, with a significant difference between the survival curves (p=0.048).

 

Conclusion: The HF ablations produced larger ablation margins and had fewer local progressions compared to the LF ablations.

Key Words
Authors
All
Author's Corner
Reviewer's Corner
Survey
Copyright © Turkish Society of Radiology | Latest Update: 01.11.2017