ISSN 1305-3825 | E-ISSN 1305-3612
Interventional Radiology - Original Article
Diagnostic accuracy and safety of CT-guided fine needle aspiration biopsy of pulmonary lesions with non-coaxial technique: a single center experience with 442 biopsies
1 Department of Radiology, Ankara University School of Medicine, Ankara Turkey  
2 Department of Biostatistics, Ankara University School of Medicine, Ankara Turkey  
3 Department of Cytopathology, Ankara University School of Medicine, Ankara Turkey  
Diagn Interv Radiol ; : -
DOI: 10.5152/dir.2016.16173
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Abstract

PURPOSE: We aimed to evaluate the diagnostic accuracy and safety of computed tomography (CT)-guided biopsy of pulmonary lesions with fine needle aspiration (FNA) using non-coaxial technique.

 

METHODS: We analyzed 442 patients who underwent CT-guided lung biopsy with FNA and non-coaxial technique to determine the diagnostic outcomes, complication rates, and independent risk factors for diagnostic failure and pneumothorax.

 

RESULTS: Diagnostic accuracy, sensitivity, and specificity were 97.6%, 97.3%, and 100%, respectively. Age and >35 mm lesion size were significant risk factors for diagnostic failure. The rates of pneumothorax and chest tube placement were 19% and 2.9%, respectively. Middle and lower lobe location, lesion to pleura distance >7.5 mm, and >45° needle trajectory angle were significant risk factors for pneumothorax.

 

CONCLUSION: CT-guided FNA of pulmonary lesions with non-coaxial technique is a safe and reliable method with a relatively low pneumothorax rate and an acceptably high diagnostic accuracy. 

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