E-ISSN 1305-3612
Head and Neck Imaging - Original Article
Virtual touch tissue imaging quantification shear wave elastography for determining benign vs malignant cervical lymph nodes: a comparison with conventional ultrasound
Diagn Interv Radiol ; : -

Abstract

PURPOSE: The aim of this study was to prospectively examine virtual touch tissue imaging quantification (VTIQ) shear wave elastography (SWE) and conventional (B mode and Doppler) ultrasound, individually and combined, for their ability to differentiate benign and malignant cervical lymph nodes (CLNs).

 

METHODS: One hundred enlarged lymph nodes from 72 patients, confirmed by histopathologically diagnoses, were included in this study. B-mode US, Doppler US and SWE were performed before histopathological sampling of lymph nodes. The lymph node shear wave velocity (SWV, m/s) was assessed by VTIQ.

 

RESULTS: Using 3.03 m/sn cut off value, the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of SWVmax for differentiating benign and malignant CLNs were 93%, 59%, 68%, 91% and 75%, respectively. B-mode and Doppler had a sensitivity, specificity, PPV, NPV and accuracy of 79.2% , 71.2%, 71.6%, 78.7%, and 75% respectively. B-mode, Doppler, and VTIQ SWE combined had 87.5% , 75%, 76.3%, 86.6% and 81% for the same parameters, respectively.

 

CONCLUSION: VTIQ SWE is a promising noninvasive diagnostic imaging technique for differentiating benign and malignant CLNs. VTIQ SWV can improve the diagnostic performance of conventional US for differentiating benign and malignant CLNs.

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