E-ISSN 1305-3612
Abdominal Imaging - Original Article
Diffusion-weighted MRI of urinary bladder and prostate cancers
1 From the Department of Radiology, Bakırköy Dr. Sadi Konuk Training and Research Hospital, İstanbul, Turkey  
2 Department of Radiology, Namık Kemal University School of Medicine, Tekirdağ, Turkey  
3 Department of Radiology, University of Yeditepe School of Medicine, İstanbul, Turkey  
4 Departments of Radiology, 19 Mayıs University School of Medicine, Samsun, Turkey  
Diagn Interv Radiol 2009; 15: 104-110

Key Words: diffusion magnetic resonance imaging • urinary bladder • prostate

The purpose of this study was to evaluate the feasibility of diffusion-weighted imaging in the diagnosis of the urinary bladder and prostate carcinomas. The apparent diffusion coefficient (ADC) values of the malignant and normal tissues were correlated.


A total of 23 patients with 14 urinary bladder carcinomas and 9 prostate carcinomas, and 50 healthy controls with normal ultrasonographic urinary bladder and prostate gland imaging findings were enrolled in the study. The ADC values were reported as the mean ± standard deviation. Student's t test was performed to compare the ADC values of the normal and pathological tissues. Diffusion-weighted imaging (DWI) was performed with b factors of 0, 500, and 1000 s/mm2, and the ADC values of the normal tissues and lesions were calculated.


The mean ADC value of the urinary bladder wall of the control group and bladder carcinomas were (2.08 ± 0.22x10-3 mm2/s) and (0.94 ± 0.18x10-3 mm2/s), respectively. In addition, the ADC values of the normal peripheral (2.07 ± 0.33x10-3 mm2/s), transitional zones (1.46 ± 0.23x10-3mm2/s) of the prostate, seminal vesicles (2.13 ± 0.13x10-3 mm2/s) and the prostate carcinomas (1.06 ± 0.17x10-3mm2/s) were calculated. The comparison of mean ADC values of the peripheral-transitional zones of the prostate, normal bladder wall-bladder carcinomas, and peripheral zone prostate carcinomas were statistically significant (P < 0.01).


The present study demonstrated that ADC measurement has a potential ability to differentiate carcinomas from normal bladder wall and prostate gland.

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