ISSN 1305-3825 | E-ISSN 1305-3612
Musculoskeletal Imaging - Original Article
Diffusion tensor imaging in carpal tunnel syndrome
1 Department of Radiology, University of Yeditepe School of Medicine, İstanbul, Turkey  
2 Department of Radiology, Yeditepe University School of Medicine, İstanbul, Turkey  
3 From the Department of Radiology, Bakırköy Dr. Sadi Konuk Training and Research Hospital, İstanbul, Turkey  
4 Department of Radiology, University of North Carolina, Chapel Hill, ABD.  
5 Departments of Neurology, Yeditepe University School of Medicine, İstanbul, Turkey  
6 Department of Plastic Reconstructive and Aesthetic Surgery, Haydarpaşa Numune Teaching and Research Hospital, İstanbul, Turkey  
7 Department of Biomedical Engineering, Yeditepe University School of Engineering, İstanbul, Turkey  
8 Departments of Radiology, Yeditepe University School of Medicine, İstanbul, Turkey  
Diagn Interv Radiol 2012; 18: 60-66
DOI: 10.4261/1305-3825.DIR.3994-10.1
Key Words: carpal tunnel syndrome • diffusion tensor imaging• median nerve • median neuropathy
Abstract

PURPOSE
We aimed to investigate the efficacy of diffusion tensor imaging in the diagnosis of carpal tunnel syndrome and to obtain a quantitative parameter that may contribute to the diagnosis.

 

MATERIALS AND METHODS
The median nerves in 57 wrists of 38 patients diagnosed as carpal tunnel syndrome and 30 wrists of 24 normal subjects were prospectively evaluated with a 3T Philips scanner, using standard 8-channel SENSE head coil. Diffusion tensor imaging was performed using spin echo-echo planar imaging. For anatomical reference, a T1-weighted sequence was acquired. Fractional anisotropy and apparent diffusion coefficient measurements were done focally at the carpal tunnel level and from whole median nerve.

 

RESULTS
In carpal tunnel syndrome patients, both focal carpal tunnel and whole nerve measurements demonstrated statistically significantly lower fractional anisotropy values than normal subjects (P < 0.001). No statistically significant difference was observed in apparent diffusion coefficient measurements. The cut-off value obtained by receiver operator characteristics analysis was 0.554 for focal carpal tunnel fractional anisotropy (sensitivity, 80%; specificity, 80%) and 0.660 for whole nerve fractional anisotropy (sensitivity, 82%; specificity, 80%) measurement.

 

CONCLUSION
Diffusion tensor imaging may contribute to the diagnosis of carpal tunnel syndrome on the basis of fractional anisotropy measurements.

Key Words
Authors
All
Author's Corner
Reviewer's Corner
Survey
Copyright © Turkish Society of Radiology | Latest Update: 01.11.2017