ISSN 1305-3825 | E-ISSN 1305-3612
Critical limb ischemia: an update for interventional radiologists
1 Department of Vascular Imaging and Intervention, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA  
2 Department of Imaging, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal  
3 Department of Radiology, Kalispell Regional Medical Center, Kalispell, Montana, USA  
4 Department of Vascular Imaging and Interventions Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA  
5 Department of Vascular Imaging and Interventions, Harvard University Medical School, Massachusetts General Hospital, Massachusetts, USA  
Diagn Interv Radiol 2013; 19: 173-180
DOI: 10.4261/1305-3825.DIR.5955-12.1
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Critical limb ischemia (CLI) is a growing epidemic with bleak patient outcomes. A variety of treatment modalities have been adopted to address CLI based on comorbidities, life expectancy, and the nature of the arterial disease. With advances in technology and treatment strategies, the clinical outcomes of CLI patients have significantly improved over recent years. However, despite progress, patency rates of both surgical and endovascular interventions, limb-salvage and amputation rates are still dismal. We review the epidemiology, treatment strategies, imaging modalities, and the microcirculation aspect of CLI.

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