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March / April 2013, Volume 19, Issue 2, Page(s) 173-180
Critical limb ischemia: an update for interventional radiologists
Nicholas F. Brazeau1, Erique G. Pinto2, Harlan B. Harvey1, George R. Oliveira1, Benjamin J. Pomerantz3, Stephan Wicky1, Rahmi Oklu1
1Department of Vascular Imaging and Intervention, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
2Department of Imaging, Hospital Professor Doutor Fernando Fonseca, Amadora, Portugal
3Department of Radiology, Kalispell Regional Medical Center, Kalispell, Montana, USA
DOI: 10.4261/1305-3825.DIR.5955-12.1
Critical limb ischemia (CLI) is a growing epidemic with bleak patient outcomes. A variety of treatment modalities have been adopted to address CLI based on comorbidities, life expectancy, and the nature of the arterial disease. With advances in technology and treatment strategies, the clinical outcomes of CLI patients have significantly improved over recent years. However, despite progress, patency rates of both surgical and endovascular interventions, limb-salvage and amputation rates are still dismal. We review the epidemiology, treatment strategies, imaging modalities, and the microcirculation aspect of CLI.