doi: 10.4261/1305-3825.DIR.3049-09.1

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Assesment of ovarian stromal artery Doppler characteristics and serum hormone levels in patients with Behçet’s Disease
Aylin Pelin Cil1, Ayse Anil Karabulut2, Mukadder Kocak2
1Kırıkkale University School of Medicine, Obstetrics and Gynecology, Kırıkkale, Turkey
2Kırıkkale University School of Medicine, Dermatology, Kırıkkale, Turkey

Purpose: The aim of the study was to examine serum hormone levels, ovarian volume, stromal artery Doppler parameters of patients with Behçet’s disease (BD) to assess whether there is vascular changes in the gonads of these patients. Materials and Methods: Twenty patients with BD and 31 healthy controls aged between 18-45 years were examined in the early follicular phase of the menstrual cycle (day 2-3) with transvaginal ultrasound to evaluate ovarian volume and ovarian stromal artery Doppler parameters. On the same day, blood was drawn for determining serum hormone levels. Results: Patients with BD and the controls were comparable with regard to age and body mass index at study inclusion. Although comparison of the ovarian stromal artery Doppler velocimetric parameters did not show significant differences, resistivity, pulsatility indexes and systolic/diastolic ratio were higher, while peak systolic and end diastolic velocities were lower in BD patients compared to controls. The mean ovarian volume of patients with BD was smaller than the controls but this difference did not reach statistically significance. There were no stastistically significant differences between serum hormone levels of both groups. We did not find any correlations between hormone levels and mean ovarian stromal artery Doppler parameters of patients with BD. Conclusion: Ovarian stromal artery Doppler parameters of patients with BD did not show any significant differences compared to healthy controls. Therefore, we conclude that ovarian stromal artery is not involved in patients with BD as assessed by transvaginal Doppler ultrasound and serum hormone levels do not differ from the levels of healthy controls.

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