Interventional Radiology - Original Article

Effectiveness of percutaneous vertebroplasty in patients with multiple myeloma having vertebral pain


  • Ömer Fatih Nas
  • Mehmet Fatih İnecikli
  • Kadir Hacıkurt
  • Ramazan Büyükkaya
  • Güven Özkaya
  • Fahir Özkalemkaş
  • Rıdvan Ali
  • Cüneyt Erdoğan
  • Bahattin Hakyemez

Received Date: 22.05.2015 Accepted Date: 07.09.2015 Diagn Interv Radiol 2016;22(3):263-268


We aimed to assess the effectiveness, benefits, and reliability of percutaneous vertebroplasty (PV) in patients with vertebral involvement of multiple myeloma.


PV procedures performed on 166 vertebrae of 41 patients with multiple myeloma were retrospectively evaluated. Most of our patients were using level 3 (moderate to severe pain) analgesics. Magnetic resonance imaging was performed before the procedure to assess vertebral involvement of multiple myeloma. The following variables were evaluated: affected vertebral levels, loss of vertebral body height, polymethylmethacrylate (PMMA) cement amount applied to the vertebral body during PV, PMMA cement leakages, and pain before and after PV as assessed by a visual analogue scale (VAS).


Median VAS scores of patients decreased from 9 one day before PV, to 6 one day after the procedure, to 3 one week after the procedure, and eventually to 1 three months after the procedure (P < 0.001). During the PV procedure, cement leakage was observed at 68 vertebral levels (41%). The median value of PMMA applied to the vertebral body was 6 mL.


Being a minimally invasive and easily performed procedure with low complication rates, PV should be preferred for serious back pain of multiple myeloma patients.