Diagnostic and Interventional Radiology
Abdominal Imaging - Review

Abdominal sarcoidosis: cross-sectional imaging findings

1.

Department of Radiology, School of Medicine, Dokuz Eylul University, Izmir, Turkey

2.

Department of Radiology, School of Medicine, Ege University, Izmir, Turkey

3.

Department of Pathology, Centre Hospitalier Paris Sud, Paris, France

4.

Department of Radiology, School of Medicine, Pamukkale University, Denizli, Turkey

Diagn Interv Radiol 2015; 21: 111-117
DOI: 10.5152/dir.2014.14210
Read: 661 Downloads: 274 Published: 03 September 2019

Abstract

Sarcoidosis is a multisystem inflammatory disease of unknown etiology. The lungs and the lymphoid system are the most commonly involved organs. Extrapulmonary involvement is reported in 30% of patients, and the abdomen is the most common extrapulmonary site with a frequency of 50%–70%.

Although intra-abdominal sarcoidosis is usually asymptomatic, its presence may affect the prognosis and treatment options. The lesions are less characteristic and may mimick neoplastic or infectious diseases such as lymphoma, diffuse metastasis, and granulomatous inflammation. The liver and spleen are the most common abdominal sites of involvement. Sarcoidosis of the gastrointestinal system, pancreas, and kidneys are extremely rare. Adenopathy which is most commonly found in the porta hepatis, exudative ascites, and multiple granulomatous nodules studding the peritoneum are the reported manifestations of abdominal sarcoidosis.

Since abdominal sarcoidosis is less common and long-standing, unrecognized disease can result in significant morbidity and mortality. Imaging contributes to diagnosis and management of intra-abdominal sarcoidosis. In this report we reviewed the cross-sectional imaging findings of hepatobiliary, gastrointestinal, and genitourinary sarcoidosis.

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