Diagnostic and Interventional Radiology
Abdominal Imaging - Original Article
Hyperintensity at fat spared area in steatotic liver on the hepatobiliary phase MRI

Hyperintensity at fat spared area in steatotic liver on the hepatobiliary phase MRI

1.

Department of Radiology, Hacettepe University School of Medicine, Ankara, Turkey

Diagn Interv Radiol 2019; 25: 416-420
DOI: 10.5152/dir.2019.18535
Read: 349 Downloads: 199 Published: 04 November 2019

PURPOSE

We aimed to investigate the reasons for hyperintensity at fat spared area in steatotic liver at hepatobiliary phase (HBP) on gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid (Gd-EOB-DTPA) enhanced liver magnetic resonance imaging.

 

METHODS

Twenty-two patients with focal fat spared area demonstrating hyperintensity on HBP images were included. A region of interest was placed on in- and opposed-phase images at fat spared area and liver to measure the fat. The measurement was also performed on precontrast T1-weighted and HBP images. The signal intensities of spleen, kidney, muscle, intervertebral disc, and spinal cord were also recorded.

 

RESULTS

The mean fat fraction of liver and fat spared area was 24.86% (8%–46%) and 8.41% (1%–34%), respectively (P < 0.001). There was a significant positive correlation between liver parenchyma fat fraction and delta fat fraction (r=0.74, P < 0.001). The mean signal intensity values of fat spared areas were higher compared with liver on precontrast T1-weighted and HBP images (P < 0.001). The mean relative enhancement ratio of liver and fat spared areas were 0.98 (0.05–1.90) and 1.15 (0.22–2.03), respectively (P < 0.001). However, in 6 patients, the relative enhancement ratio of liver and fat spared areas were almost equal. The uptake of Gd-EOB at fat spared area was not correlated with the degree of steatosis (r = -0.01, P = 0.95).

 

CONCLUSION

Fat spared area in steatotic liver appears hyperintense on HBP images due to increased relative enhancement ratio and/or baseline hyperintensity on precontrast images.

 

You may cite this article as: Ünal E, İdilman İS, Karaosmanoğlu AD, Özmen MN, Akata D, Karcaaltıncaba M. Hyperintensity at fat spared area in steatotic liver on the hepatobiliary phase MRI. Diagn Interv Radiol 2019; 25:416–420.

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