Diagnostic and Interventional Radiology
Interventional Radiology - Technical Note

Technical aspects of renal denervation in end-stage renal disease patients with challenging anatomy

1.

Department of Diagnostic Imaging, Molecular Imaging, Interventional Radiology, and Radiation Therapy, University Hospital “Tor Vergata”, Rome, Italy.

2.

Department of Internal Medicine, Nephrology, and Hypertension, University Hospital “Tor Vergata”, Rome, Italy.

Diagn Interv Radiol 2014; 20: 267-270
DOI: 10.5152/dir.2013.13408
Read: 229 Downloads: 86 Published: 03 September 2019

Abstract

We describe our preliminary experience with percutaneous renal denervation in end-stage renal disease patients with resistant hypertension and challenging anatomy, in terms of the feasibility, safety, and efficacy of this procedure. Four patients with end-stage renal disease patients with resistant hypertension (mean hemodialysis time, 2.3 years) who had been taking at least four antihypertensive medications underwent percutaneous renal denervation. Renal artery eligibility included the absence of prior renal artery interventions, vessel stenosis <70%, or extended calcifications (more than 30% of the vessel circumference). No cut off values of vessel diameter were used. All patients were successfully treated with no intra- or postprocedural complications, and all showed 24-hour ambulatory blood pressure reduction at the 12-month follow-up. Percutaneous renal denervation is a feasible approach for end-stage renal disease patients with resistant hypertension with encouraging short-term preliminary results in terms of procedural efficacy and safety.

Files
EISSN 1305-3612
3