Diagnostic and Interventional Radiology
Abdominal Imaging - Original Article

The effect of MWA protocols upon morphology and IVIM parameters of hepatic ablation zones—a preliminary in vivo animal study with an MRI-compatible microwave ablation device

1.

Department of Radiology, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangdong, People’s Republic of China

2.

Department of Radiology, 82 Group Hospital of PLA, Hebei, Province, People’s Republic of China

3.

Department of Radiology, the Third Affiliated Hospital of Sun Yat-Sen University, Guangdong, People’s Republic of China

4.

Department of Interventional Radiology, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangdong, People’s Republic of China

Diagn Interv Radiol 2022; 28: 115-123
DOI: 10.5152/dir.2022.20292
Read: 519 Downloads: 86 Published: 01 February 2021

PURPOSE

We aimed to explore the effect of microwave ablation (MWA) protocols upon morphology and instant changes in intravoxel incoherent motion (IVIM) diffusion-weighted imaging (DWI) parameters on MWA zones in porcine livers.

METHODS

According to the empirical protocol for MWA in tumors less than 3 cm in our hospital, the power and application duration were assigned as five groups: A, 60 W × 5 min (n = 6); B, 80 W × 3 min (n = 7); C, 80 W × 5 min (n = 10); D, 100 W × 3 min (n = 10); E, 100 W × 5 min (n = 9). Spearman correlation between MWA protocols, morphological metrics, and instant post-ablation IVIM parameters was performed.

RESULTS

There was fair positive correlation between energy delivery and short axis (RSpearman = 0.426, P= .005) of the white zone. There was moderate-to-good positive correlation between wattage and short axis (RSpearman = 0.584, P < .001) of the white zone. For post-ablation IVIM parameters in the white zone, only wattage had moderate-to-good positive correlation with D value (RSpearman= 0.574, P < .001) or ADC value (RSpearman = 0.550, P < .001). No correlation between energy delivery, wattage, duration, and f value was observed (RSpearman = 0.185, P = .24; RSpearman= − 0.001, P = .99; RSpearman = 0.203, P = .20, respectively).

CONCLUSION

The increase in the short axis of the white zone is more likely to be affected by wattage than energy delivery. The instant post-ablation IVIM is feasible in monitoring the MWA zones since the f value in the white zones is not sensitive to changes in MWA protocols, which is promising in evaluating the instant effect of MWA.

You may cite this article as: Ye W, Yang W, Guo C, Dong C, Shi F, Liang C. The effect of MWA protocols upon morphology and IVIM parameters of hepatic ablation zones—a preliminary in vivo animal study with an MRI-compatible microwave ablation device. Diagn Interv Radiol. 2022;28(2):115-123.

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