E-ISSN 1305-3612
Cardiovascular Imaging - Original Article
Ultra-low dose contrast CT pulmonary angiography in oncologic patients using a high-pitch helical dual source technology
1 Department of Radiology, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA; Department of Radiology, Cardiothoracic Imaging, UT Southwestern Medical Center, Dallas, Texas, USA  
2 Department of Radiology, University Hospitals Cleveland Medical Center, Cleveland; Rebecca D. Considine Research Institute, Akron Children’s Hospital, Akron, Ohio, USA  
3 Department of Radiology, University Hospitals Cleveland Medical Center, Cleveland, Ohio; Department of Radiology, University of Chicago, Chicago, Illinois, USA  
Diagn Interv Radiol ; : -


Purpose: To determine if the image quality and vascular enhancement are preserved in CTPA studies performed with ultra-low contrast and optimized radiation dose using high-pitch helical mode of a second generation dual source scanner.

: We retrospectively evaluated oncologic patients who had CTPA on a 128-slice Dual-source scanner, with a high-pitch helical mode (3.2), following injection of 30 ml of Ioversal at 4 mL/sec with BMI dependent tube potential (80- 120 kVp) and current (130-150 mAs). Attenuation, noise and Signal-to-noise ratio (SNR) were measured in multiple pulmonary arteries. Three independent readers graded the images on a 5-point Likert scale for central vascular enhancement (CVE), peripheral vascular enhancement (PVE) and overall quality (IQ). Results from this study were compared with values reported in the literature.

: There were 50 males and 101 females in our study. BMI ranged from 13 to 38(22.8±4.4). PE was present in 29 (18.9 %). Contrast enhancement and SNR were excellent in all the pulmonary arteries (395.3±131.1 & 18.3±5.7, respectively). Image quality was considered excellent by all the readers, with average reader scores (CVE= 4.83 ± 0.48, PVE=4,68 ± 0.65, Noise/Quality 4.78±0.47) near the highest possible score of 5.0.  The average radiation dose (DLP) is 161±60 mGy.cm.

: Using a helical high-pitch acquisition technique, CTPA images of excellent diagnostic quality, including visualization of peripheral segmental/sub-segmental branches can be obtained using an ultra-low dose of iodinated contrast and low radiation dose.

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